Sedative

Quick Facts

Description: Sedatives are substances that promote relaxation, calmness, and sleep. They have a calming effect on the central nervous system, reducing excitability and promoting drowsiness.

Mechanism of Action: Sedatives generally work by enhancing the effects of GABA (gamma-aminobutyric acid), a major inhibitory neurotransmitter in the brain. GABA reduces neuronal excitability throughout the nervous system. By increasing GABA activity, sedatives decrease brain activity, leading to relaxation, drowsiness, and, at higher doses, sleep. Some sedatives may also affect other neurotransmitter systems, such as serotonin or dopamine. The specific mechanism varies depending on the sedative.

Common Uses: Sedatives are used to treat insomnia, anxiety, and muscle spasms. They are also used before medical procedures to induce relaxation and reduce anxiety. Examples of herbs with sedative properties include Valerian root, Passionflower, Chamomile, and Lavender. *It is crucial to use sedatives responsibly and under the guidance of a healthcare professional, as they can be habit-forming and have potential side effects and interactions.*